In simple terms, cannabis tolerance is essentially an adaptation by the body that results in a reduction in the effects of cannabis. It develops in all regular cannabis users, and can start to set in after only a few days of consecutive use. Within our bodies, tolerance develops through two physiological pathways. The first develops at the cellular level, where a couple things can happen: 1) down-regulation of CB1 receptors in the brain (body makes less cannabinoid receptors), and/or 2) uncoupling of the biological pathway (so even if THC binds to CB1, the signal is not transmitted any further). These mechanisms are tightly controlled by the body and will require a tolerance break to "reset."
The secondary pathway occurs at the organ level (absorption/elimination). This is where a product like Enhanced Effect™ can be of benefit. In this way, we can help regular users go longer periods of time before a needing tolerance break. So in any person who's developed tolerance mainly through this secondary pathway,
By helping patients reduce tolerance to cannabis, they can maximize its medicinal benefits. They can also use cannabis continuously, without the need to take "tolerance breaks"--which was previously the only way to reduce tolerance. A proper tolerance break lasts 2-4 weeks--that's a long time to go without medicine when you depend on it daily.